- Women having pelvic infection or repeated UTI
- Previous cesarean section
- History of intestinal surgery or infection
- Stage 4 endometriosis
- Bilateral hydrosalpinx
- Pelvic tuberculosis
- Bleeding disorders
- Undergoing PGD
- Contraindication for IVF/ICSI
- Any diseases of endometrium like fibroids, septum, polyp
What are the modes of endometrial stimulation?
Endometrial scratching enhances uterine receptivity by multiple means:
1. Stimulation of the endometrium at the site of injury causes favourable changes in the local area.This in turn increases factors of implantation for a successful pregnancy.
2. Repair process following scratching and trauma invites cells of inflammation to the site. Various inflammatory cytokines and growth factors exert a positive effect on implantation. In high concentrations these factors exert a positive outcome in the implantation window.
3. Hyperstimulation of ovaries during IVF treatment causes advanced endometrial maturation. Endometrial stimulation in this cycle may help synchronize embryo development and endometrial preparation.
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