- Hormone therapy for Ovarian Stimulation: A woman is born with approximately 500,000 immature eggs. Several of them begin to develop every month beginning with puberty, but only one reaches the final level of development. Others deteriorate. This is how a woman naturally releases a mature oocyte during her menstrual period. The ovaries are stimulated by the hormone treatment so that all of the oocytes that have begun to develop can mature without degenerating. As a result, many mature eggs can be obtained in the same cycle. Ovarian stimulation drugs are provided by subcutaneous injections. Hormones, particularly gonadotropin, follicle stimulating hormone (FSH), and/or luteinizing hormone (LH), stimulate egg formation and growth. GnRH analogues are also administered to improve hormone regulation and avoid spontaneous ovulation, which would cause the cycle to be cancelled. The exact protocol of this treatment will differ depending on the donor’s condition and the peculiarities of her menstrual cycle. The donor will adhere to the doctor’s instructions from the first day of her menstruation, or the first day of the menstrual cycle, until the time specified by the specialist. She is instructed on how to take the drug so that she no longer has reservations and the treatment is more successful. Treatment normally lasts no more than 10-12 days.
Hormonal treatment injection for Egg Donation Process: During the hormonal stimulation, the donor visits the clinic every 2 days to have the appropriate ultrasound and analytical tests performed:
- Estrogen Level: The release of estrogen rises as the oocytes mature. This is why their concentration rises in the donor’s blood.
- Follicle Size: The follicle expands in size as the oocyte grows and matures. When the follicle reaches roughly 16-18 mm in diameter, it signals that ovulation is approaching, indicating that the oocytes are developed and ready to be harvested. The specialist uses these analyses to study the growth of the ovary in order to determine the stage of oocyte maturation. To collect them, the puncture is set to occur before natural ovulation.
- Follicular Puncture: Follicular puncture, often known as ovarian puncture, is a surgical operation used to remove oocytes. It takes roughly 20-30 minutes and is conducted under general anaesthesia. An ultrasound-guided puncture is used to remove the fluid containing the egg from the follicles into a needle. Aspiration is accomplished through the vagina. As a result, the donor will bear no scars from the operation. She will require a brief stay in the recovery room before being released to go home on her own. She may have some discomfort, but waking up will be painless. Once at home, the donor can resume normal activities, but she is urged not to exert too much effort in the first few days. The cycle will resume normally about two weeks following the puncture, with the return of menstruation.