What is the cause of anovulation?

Causes of anovulation

If you are getting negative ovulation test results, you might experience it due to any of the following:

Polycystic Ovary Syndrome (PCOS)

  • It is a common endocrine disorder experienced by women in their reproductive years. It is also the most common cause of anovulatory infertility.
  • In women with PCOS, there is a raised concentration of Luteinizing Hormone (LH), testosterone, and androstenedione, in association with low or normal levels of follicle stimulating hormone (FSH).

Low BMI

  • Women who have a low BMI due to illnesses, anorexia nervosa or excessive exercise experience amenorrhea.
  • If you are experiencing this, leptin that is secreted from fat prevents pulses of gonadotropin-releasing hormone (GnRH) to be released by hypothalamus.
  • Although BMI is not an overall indicator of health, studies show that infertility could sometimes be associated with higher and lower BMI.

Medications

  • If you are on birth control pills or oral contraceptives, you might not ovulate.

Stress 

  • You might not ovulate if you are experiencing chronic stress. 
  • Stress-induced anovulation (SIA) hinders the secretion of GnRH.
  • Certain behavioral changes in your body could lead to stress.

Hypothalamic Lesions

  • Tumors, inflammation, and lesions of the hypothalamus can also cause anovulation.

Menopause 

  • If you attain early menopause before the age of 45, you will not ovulate. 
  • You might experience certain menopausal symptoms like hot flashes, night sweats, vaginal dryness, low mood or anxiety.

It is important that you understand the symptoms and the ways in which anovulation can manifest in your body. 

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