What is Paternal Lymphocyte Immunization (PLI)?

In Paternal Lymphocyte Immunization (PLI), white blood cells from the intended father are separated from his blood and injected into the mother. Given that both the mother’s and the father’s genes are present in pregnancy tissues, PLI (LIT) Therapy helps the mother’s immune system build immunologic tolerance to the genetically alien pregnancy tissues. If a woman has had several miscarriages or failed IVF attempts, she may benefit from this treatment. Immunological issues are typically a cause for these miscarriages or failures.