Implantation is the deciding step in successful pregnancy and requires a receptive endometrium. In a small number of cases an embryo doesn’t implant because of a hostile endometrial lining. In other words, the endometrium of the uterus does not provide the right environment for the embryo. This failed embryonic implantation is due to endometrial receptivity disorder. Endometrial receptivity depends on the signals from various chemical messengers. Dysregulation of these molecules causes implantation failure. Thickness of endometrium, immunity status, adhesive molecules all play a role in receptivity disorder. Endometrial stimulation or scratching may improve these factors.
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