What are the Causes of Primary Ovarian Insufficiency?

The precise causes of POI are not always known, but several factors can contribute to its development:

• Genetic Factors: Certain genetic disorders can cause POI or make a person more susceptible to developing it.
  
• Autoimmune Disorders: The immune system may mistakenly attack the ovaries, disrupting their function.
  
• Chemotherapy and Radiation: Cancer treatments like chemotherapy and radiation therapy can damage the ovaries, leading to POI.
  
• Ovarian Surgery: Surgical procedures involving the ovaries may inadvertently cause damage, affecting their functionality.
  
• Toxins and Environmental Factors: Exposure to certain chemicals or environmental toxins can also play a role in the development of POI.