Obesity, Type 2 Diabetes, PCOS Increase Your Risk of Insulin Resistance

Women whose mother or sister has PCOS or type 2 diabetes are more likely to develop PCOS. Lifestyle can have a big impact on insulin resistance, especially if a woman is overweight because of an unhealthy diet and lack of physical activity. Insulin resistance also runs in families insulin resistance forms a central cornerstone of the pathogenesis of PCOS and mediates a close association between obesity and the severity of the phenotypic features of PCOS