How to prepare for an ERA

The ERA cycle takes about four weeks to complete from initial testing to when results are available. The cycle itself takes about 16 days, then allow an additional 14 days to receive results.  An ERA cycle is performed the same way a patient prepares for a frozen embryo transfer (FET). However, rather than performing an actual embryo transfer, an endometrial biopsy is performed. The biopsy assesses whether the uterine lining would have been receptive if an embryo transfer was performed.  

What can patients expect during the ERA testing process? 

1. Estrogen) pills are taken for 10 days, or until the lining measures at least 7mm and Estrogen levels are adequate.

2. Progesterone is then prescribed for 6 days. Receptivity to implantation depends on the length of time exposed to progesterone.

3. A subset of patients may benefit from longer or shorter timelines of progesterone exposure.

4. An endometrial biopsy is performed, and the lab then analyzes tissue samples for more than 200 genes to predict the best time to transfer the embryo into the uterus.

5. The FET protocol and length of progesterone exposure is then adjusted to align with the most optimal time to transfer an embryo.

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