Antiphospholipid Antibody Syndrome (APS) and pregnancy

Antiphospholipid Antibody Syndrome causes huge clotting of the blood. It increases the mother’s risk of developing hypertension and increases the baby’s risk of IUGR, miscarriage, and stillbirth.A pregnant patient with the antiphospholipid syndrome can be treated with low-dose aspirin and anticoagulants throughout the pregnancy, until about six weeks after childbirth which can decrease clotting as well as the risk of complications.APS is caused by autoantibodies to certain phospholipid-binding proteins that would protect against excessive coagulation activation.

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