Discovering the particular causes of cryptozoospermia is a considerably difficult task. In most cases, the man is unaware that he has this sperm disorder until he starts trying to conceive.However, the potential causes can be classified into the following groups depending on their origin:
- Pre-testicular causesalter the hormonal regulation of spermatogenesis, including conditions such as hypogonadism, or unhealthy habits (tobacco, alcoholic drinks, environmental toxics, etc.).Testicular causesaffecting the testicles directly, including cryptorchidism, hydrocele, trauma, varicocele.Post-testicular causescausing obstructive cryptozoospermia, as they prevent the expulsion of sperm to the exterior. Examples include ejaculatory duct obstruction, absence of ejaculatory ducts, vasectomy, and urethritis (inflammation of the urethra).