The following are the most typical justifications for aided hatching in an IVF case: Although assisted hatching is not advised for everyone, it may be beneficial for women who are older (over 37) or have experienced IVF failure in the past.
- Age factor: The female partner is older than 37 due to age.
- Egg quantity and quality factor: situations where a woman’s day 3 follicle stimulating hormone (FSH) level is high, or when she has low antral follicle count, AMH level, or all three.
- Embryo quality factor: situations where the embryos are of poor quality (high cell division rates or severe fragmentation)
- Zona factor: Embryos with a thick outer shell (zona pellucida) are referred to as having the zona factor.
- Previous IVF failure: situations in which one or more IVF attempts had previously failed.