AMH levels fail to follow the endocrine fluctuations that are so typical for the menstrual cycle. In the human ovary, AMH is mainly produced by granulosa cells of small antral follicles sized 2–6 mm. within the normal menstrual cycle, the variability of AMH levels is extremely small. Therefore, a single measurement of AMH obtained at any time in the menstrual cycle may be considered a valid reflection of a woman’s ovarian reserve.
